a-PVP Analog


alpha-PVP ( a-pvp analog ) is the ketone analog of prolintan, another stimulant, psychoactive substance that belongs to the cathinones.

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alpha-PVP is the ketone analog of prolintan, another stimulant, psychoactive substance that belongs to the cathinones.

Andere Namen: a-PVP, α-PVP, alpha-PVP, alpha-Pyrrolidinopentiophenon, alpha-Pyrrolidinopentiophenone (engl.), α-Pyrrolidinopentiophenon, α-Pyrrolidinopentiophenone (engl.), O-2387, ß-keto-prolintan, ß-keto-prolintane (engl.), Prolintanon, Prolintanone (engl.), Desmethyl Pyrovaleron, Desmethyl Pyrovalerone (engl.), Flakka, Gravel, 2-(1-pyrrolidinyl)-Valerophenon, 2-(1-pyrrolidinyl)-Valerophenone (engl.)

IUPAC: (RS)-1-Phenyl-2-(1-pyrrolidinyl)-1-pentanon, (RS)-1-Phenyl-2-(1-pyrrolidinyl)-1-pentanone (engl.)

Summenformel: C15H21NO

Molekulare Masse: 231.333 g/mol


a-PVP – There is not enough information about this substance!

Hardly any reports from consumers and certainly very few scientific papers.
Accordingly, the consumption is an unpredictable risk, possible toxic effects may be undetected.
We strongly advise against taking it! The following information is a collection of information taken from reports about this designer drug. We can not guarantee the accuracy and recommend to anyone to consult further sources.

Effect of a-PVP

The effects and side effects listed here are all very subjective and are perceived differently by each person.
They do not always have to occur and there may be other, unmentioned effects. (Then we would be pleased about a comment on this!)

These lists should not serve as a guarantee, but as a guide.

Stimulation (stimulating, awakening) – alpha-PVP has a very strong stimulating effect, many consumers feel compelled to move or perform repetitive actions. Even more stimulating than, for example, amphetamine, 2-FA or 2-MMC!
Concentration and performance increase – The focus is greatly enhanced by this substance.
Aphrodisiac – increasing sexual desire and delaying orgasm, aphrodisiac activity is less pronounced in a-PiHP according to some consumers than in a-PVP or MDPV, but still quite strong.
Increased Rededrang – A so-called “Laberflash”
Euphoric – a-PVP is said to be less euphoric than MDPV, comparable to the euphoria of amphetamine or methamphetamine, perhaps. Depending on the set & setting and tolerance, the euphoria can hardly be found!
Increased self-confidence
Improved perception of music

The effect of alpha-PVP is very similar to that of MDPV, so pyrovalerone analog typical. It is quite short and very intense, with many side effects, severe craving and more like methamphetamine than amphetamine.
Nevertheless, MDPV is much more popular than a-PVP because the euphoria in the latter should be less pronounced.

A-PVP is definitely one of the most stimulating, stimulating uppers, but also the most dangerous.

For many people, the effect is too intense and they find it very unpleasant, some like it and in those the addictiveness is very high.
It is extremely difficult to handle this substance responsibly!

a-PVP dose / dosage

These dosage indications are only approximate guidelines derived from consumer reports.
It must be started with an allergy test and a very low dose!
More Safer Use rules can be found here.


First effects from: 1-5mg
Light effect: 5-10mg
Normal: 8-25mg
Strong effect: 20-40mg
Very strong effect: 35mg +


First effects from: 0.5-1mg
Light effect: 1-5mg
Normal: 4-15mg
Strong effect: 12-25mg
Very strong effect: 20mg +


First effects from: 1-2mg
Slight effect: 2-5mg
Normal: 4-15mg
Strong effect: 12-25mg
Very strong effect: 25mg +

a-PVP reaction time


Effect on after: 5-30 minutes
Main effect: 2-6 hours
Of which peak: 1-2 1/2 hours
Coming down: 1-5 hours
Afterglow: 4-12 hours


Effect on after: 2-30 minutes
Main effect: 2-5 hours
Of which peak: 20-45 minutes
Coming down: 30-90 minutes
Afterglow: 2-4 hours


Activation after: few seconds to minutes
Main effect: 30-60 minutes
Of which peak: 3-6 minutes
Coming down: 15-30 minutes
Afterglow: 1-3 hours


a-pvp development of tolerance

Tolerance formation is probably the same for α-PVP as for most other uppers.
Already one-time consumption increases the tolerance (with higher dose naturally correspondingly stronger than with low dosage), after 3-7 days it should be again in half, after 1-2 weeks completely reduced.

There is a cross tolerance with all other dopaminergic substances (ie all uppers, eg amphetamine, MDPV, 2-FA …).

a-PVP pharmacology

Alpha-PVP acts as a noradrenaline and dopamine reuptake inhibitor (norepinephrine: IC50 = 14.2nM, dopamine: IC50 = 12.8nM), which is very similar to the mechanism of action of MDPV.

In contrast to MDPV, however, a serotonin component is missing in a-PVP (in the case of alpha-PVP this is only very weak), which may be one reason for the lower euphoria in the latter.

So far, however, there are hardly any scientific studies, especially right to the effect on humans. Less than MDPV!

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